To see product details, add this item to your cart. You can always remove it later.
FREE Returns
Added to

Sorry, there was a problem.

There was an error retrieving your Wish Lists. Please try again.

Sorry, there was a problem.

List unavailable.
Other Sellers on Amazon
Added
Sold by: EntirelyPets
Sold by: EntirelyPets
(352838 ratings)
98% positive over last 12 months
Shipping rates and Return policy
Added
Sold by: PetStoreUSA
Sold by: PetStoreUSA
(611 ratings)
100% positive over last 12 months
Shipping rates and Return policy
Added
Sold by: Amazon.com
Sold by: Amazon.com
Shipping rates and Return policy

K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 2-Mo Supply

4.5 4.5 out of 5 stars 39,582 ratings

To see product details, add this item to your cart. You can always remove it later.
FREE Returns
Available at a lower price from other sellers that may not offer free Prime shipping.
2 Pack
Large Dog only

Purchase options and add-ons


About this item

  • K9 Advantix II Large Dog 30-day treatment & prevention protects dogs 21-55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
  • Kills fleas within 12 hours of application
  • Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
  • Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
  • No prescription needed

Customer ratings by feature

Easy to use
4.2 4.2
Scent
3.7 3.7
Comfort
3.6 3.6
Sheerness
3.5 3.5

Frequently bought together

$33.98 ($16.99/Count)
In Stock
Sold by Fannys Gifts and ships from Amazon Fulfillment.
+
$32.99 ($16.50/Count)
In Stock
Sold by Fannys Gifts and ships from Amazon Fulfillment.
+
$31.49 ($15.75/Count)
In Stock
Sold by 5 Star Retailers and ships from Amazon Fulfillment.
Total price:
To see our price, add these items to your cart.
Details
Added to Cart
These items are shipped from and sold by different sellers.
Choose items to buy together.

Compare with similar items

This Item
K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 2-Mo Supply
K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 2-Mo Supply
Recommendations
NEXTSTAR Flea and Tick Prevention for Dogs, Repellent, and Control, Fast Acting Waterproof Topical Drops for Large Dogs, 1 Month Dose
dummy
K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 6-Mo Supply
dummy
K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 4-Mo Supply
dummy
Advanllent Flea and Tick Treatment for Dogs, Flea and Tick Prevention for Extra-Large Dogs, 89-132 Pounds, 3 Doses
dummy
K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 4-Mo Supply
Details
Added to Cart
Details
Added to Cart
Details
Added to Cart
Details
Added to Cart
Details
Added to Cart
Details
Added to Cart
Price-11% $33.98
List:$38.38
-10% $17.99
List:$19.99
$79.98$57.48$14.99$57.48
Delivery
Get it as soon as Monday, Apr 1
Customer Ratings
Easy to use
4.2
3.3
4.2
4.1
4.0
4.2
Value for money
3.4
1.7
3.4
3.2
3.1
3.5
Comfort
3.6
2.4
3.6
2.7
3.5
Flavor
2.1
2.8
3.3
2.7
Scent
3.7
3.7
3.2
Sold By
Fannys Gifts
PETIQ
Amazon.com
Amazon.com
kingmo Pet
Amazon.com
target audience
Dog
Dog, Dog, Dog, Dog, Dog
Dog
Dog
Dog
Dog
age range
7 weeks and older
All Life Stages
7 weeks and older
7 weeks and older
All Life Stages
7 weeks and older
scent
Unscented
Unscented
Unscented
form
Topical
Drops
Topical
Topical
Drops
Topical
volume
5 milliliters
1 quarts
4 milliliters
16 milliliters
active ingredients
Imidacloprid, Permethrin, Pyriproxyfen
Fipronil, Cyphenothrin, (S)-methoprene
Imidacloprid, Permethrin, Pyriproxyfen
Imidacloprid, Permethrin, Pyriproxyfen
Fipronil 9.8%, (S)-methoprene 8.8%, OTHER INGREDIENTS 81.4%, TOTAL 100.0%
Imidacloprid, Permethrin, Pyriproxyfen

From the manufacturer

image

image

image

image

Kills and Repels

Unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes for up to four weeks and also protects against biting flies and lice.

Same-Day Effectiveness

K9 Advantix kills fleas on dogs within 12 hours of application and prevents reinfestation.

Vet-Recommended

K9 Advantix is the leading brand in flea, tick and mosquito protection, recommended by veterinarians.

image

image

image

Application key benefits

Easy-to-apply topical solution – no hard-to-swallow pills

Easy Application - Step 1

Holding the tube upright and pointed away from you and your pet, remove the cap from the applicator tube. Turn the cap around, place it back on the tube and twist to break the seal.

Easy Application - Step 2

Evenly apply the entire contents of the tube along the top of the dog’s back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of the dog (please refer to the product label). At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze a portion of the solution on the skin.

image
image image image image image
K9 Advantix II Large Dog Seresto Large Dog Advantage II Large Dog advantus Advantage Treatment Shampoo
Customer Reviews
4.5 out of 5 stars
39,582
4.5 out of 5 stars
99,463
4.5 out of 5 stars
4,184
4.2 out of 5 stars
12,143
4.4 out of 5 stars
1,666
Form Topical Drops Collar Topical Drops Flea Soft Chew Tick and Flea Shampoo
Treatment or Prevention Treatment + Prevention Treatment + Prevention Treatment + Prevention Treatment Treatment
Application Frequency Monthly Every 8 Months Monthly Do Not Exceed One Soft Chew in a 24-hour Period See Product Label
Kills Fleas?
Kills Ticks?
Kills Mosquitos?
Kills Lice?
Starts to Kill Fleas Within 12 hours 24 hours 12 hours 1 hour On Contact

Product guides and documents

Product details

  • Is Discontinued By Manufacturer ‏ : ‎ No
  • Product Dimensions ‏ : ‎ 1 x 4.38 x 4.75 inches; 1.6 ounces
  • Item model number ‏ : ‎ 86314940
  • Date First Available ‏ : ‎ September 1, 2014
  • Manufacturer ‏ : ‎ Elanco US Inc
  • ASIN ‏ : ‎ B00N7DEBN4
  • Customer Reviews:
    4.5 4.5 out of 5 stars 39,582 ratings

Looking for specific info?

Product Description

K9 Advantix II Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh 21-55 lbs. to use K9 Advantix II Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. And, you can stock up with 2-dose, 4-dose and 6-dose packs so you never miss a monthly treatment. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Large Dog is a trademark of Elanco or its affiliates.

Important information

Directions

Application Instructions: 1. Use only on dogs. DO NOT USE ON CATS or other animals. 2. The dog should be standing for easy application. Evenly apply the entire contents of the K9 Advantix® II tube to four to six spots on the top of the back from the shoulder to the base of the tail. 3. At each spot, part the hair until the skin is visible. 4. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. 5. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. 6. Do not get this product in your dog’s eyes, or allow your dog to ingest this product.

Customer reviews

4.5 out of 5 stars
4.5 out of 5
39,582 global ratings

Customers say

Customers like the protection and flea control provided by the pet pest control product. They mention that it repels and protects their pets from an array of things. They are also satisfied with the ease of use. However, some customers have mixed opinions on the effect on skin, value, effect on ticks, effect of dog, and quality.

AI-generated from the text of customer reviews

723 customers mention540 positive183 negative

Customers like the flea control. They say it not only takes care of fleas and ticks, but also mosquitos. Some say that it works great and has maintained flea free. Overall, most are satisfied with the product's effectiveness.

"...to this medication, and Fluke, my lab/pit mixture, remains free of fleas and ticks, all the while not exhibiting any negative symptoms...." Read more

"...It also protect against mosquitoes too frontline does not! Price is comparable to frontline." Read more

"...been continuing this prescription for more than 6months and have not seen ticks or fleas on my dogs...." Read more

"...Capstar worked as advertised but it's not a great solution - it only kills the fleas that bite the dog or cat in the 24 hours following giving the..." Read more

199 customers mention180 positive19 negative

Customers find the pet pest control product easy to use. They say it works well to repel ticks and fleas, and is easy to put on their dogs. Customers also mention that it's easy to order with a subscription.

"...than the oral tablet you get a vet prescription for and easy to order with subscription" Read more

"Easy to apply and no vet bill. Used it for 3 months on 2 dogs, so far its done everything promised." Read more

"Ease of application and it works to repel ticks and fleas" Read more

"...Easy to apply, no scent at all and didn't irritate their skin at all." Read more

73 customers mention70 positive3 negative

Customers are satisfied with the protection provided by the pet pest control product. They say it repels and protects their pets from an array of things. They also mention that it's reliable flea protection and works great for protecting their dogs from bothersome summertime bugs and associated issues. Customers also say it'll last a month and is safe enough to use even on pets with seizures.

"Advantix 2 works great. It truly repels as advertised especially the mosquitos which is good since those are the thing to worry about heartworm...." Read more

"...The repel is SO KEY! Otherwise they still have to jump on the pet and bite them for the pesticide to work...." Read more

"...It's a reliable and effective product that provides long-lasting protection against pests and is safe for use on large dogs." Read more

"Protects against an array of things. I love that it's a simple treat too give the dogs each month." Read more

1,690 customers mention1,070 positive620 negative

Customers are mixed about the quality of the pet pest control product. Some mention that it works well and very quickly, while others say that it didn't work as advertised and is completely useless.

"...This was the most effective. Within 32 hours of an application, I saw the fleas fall off...." Read more

"I’ve used frontline for years and this time it did not work! Before I could get frontline on my white boxer she got a horrible case of fleas...." Read more

"...I stand by what I stated in my previous post: this product works well for fleas, ticks, and mites in the warmer climate of middle Georgia in which..." Read more

"Advantix 2 works great. It truly repels as advertised especially the mosquitos which is good since those are the thing to worry about heartworm...." Read more

507 customers mention331 positive176 negative

Customers are mixed about the value of the pet pest control product. Some mention it's well worth the money, while others say it'd be a total waste of money.

"...Cheaper than the oral tablet you get a vet prescription for and easy to order with subscription" Read more

"...The idea of it is terrifying however, it is also expensive and for anyone struggling to spend that kind of money per month on their pup...." Read more

"...It also protect against mosquitoes too frontline does not! Price is comparable to frontline." Read more

"...It works for the time as stated on the box2) Not expensive when considering the need of the pet, and one's own sanity...." Read more

233 customers mention98 positive135 negative

Customers are mixed about the effect of the pet pest control on their skin. Some mention that it works great and does not bother their sensitive skin. However, others say that their dogs still get fleas and itches constantly.

"...I noticed toward the end of the month she got itchier and even found a flea! Three weeks in, the treatment should still have kept going...." Read more

"...This helps spread it out and not irritate her and make her itchy. Then again, my pup has allergies and she's on Zyrtec daily...." Read more

"...I love the product and recommend it but be aware that it makes their backs itchy for the first 24 hours after application...." Read more

"...Within a day of applying it my dogs stopped scratching, as always, I kept a look out in case of an adverse skin reaction as not all dogs are the..." Read more

171 customers mention95 positive76 negative

Customers are mixed about the effect of the pet pest control product. Some mention that their dogs have never had side effects with it, while others say that it can be toxic to dogs.

"...mixture, remains free of fleas and ticks, all the while not exhibiting any negative symptoms...." Read more

"...right in line with the rest of the flea med brands...expensive, dangerous, still see occasional flea...." Read more

"Dogs are healthy and never had any fleas/ticks...." Read more

"Don't give this to your pet! It is awful. It is toxic. I gave this to my dog Charlie and he was just not himself for 2-3 months...." Read more

102 customers mention37 positive65 negative

Customers are mixed about the effect of the pet pest control on ticks. Some mention that it works well and does not have any effect on tick infestation. However, others say that it does not repel ticks and does nothing to prevent them.

"...directly from FRONTLINE; indeed it was confirmed that FRONTLINE does NOT repel ticks...." Read more

"...I never saw a tick again once I started using this...." Read more

"...as it still seems effective against fleas, but since it is totally useless against ticks and has such a high rating I am issuing a one star review I..." Read more

"BE ADVISED this will NOT repel ANY tic what so ever...Have a Brittany (1 year old) that has (hopefully had after 28 days of pills) lyme decease...." Read more

No tick and fleas since we have been ordering.
5 Stars
No tick and fleas since we have been ordering.
I’ve been continuing this prescription for more than 6months and have not seen ticks or fleas on my dogs. I have a field in my backyard, and the dogs love playing outside even on rainy days. They usually would come back with ticks, in the summer especially. Since I’ve used this no more. On all 3 dogs. I have a German shepherd, shepherd mix, Chihuahua long hair. It’s only 1per package so I have to buy 3 every other month.
Thank you for your feedback
Sorry, there was an error
Sorry we couldn't load the review

Top reviews from the United States

Reviewed in the United States on February 19, 2024
Size: 2 PackStyle: Large Dog onlyVerified Purchase
3 people found this helpful
Report
Reviewed in the United States on April 29, 2012
Size: 6 PackStyle: Large Dog onlyVerified Purchase
41 people found this helpful
Report
Reviewed in the United States on March 14, 2015
Size: 6 PackStyle: Large Dog onlyVerified Purchase
128 people found this helpful
Report
Reviewed in the United States on March 5, 2024
Size: 6 PackStyle: Large Dog onlyVerified Purchase
One person found this helpful
Report
Reviewed in the United States on August 15, 2023
Size: 1 PackStyle: Large Dog onlyVerified Purchase
Customer image
5.0 out of 5 stars It worked when Frontline did not!
Reviewed in the United States on August 15, 2023
I’ve used frontline for years and this time it did not work! Before I could get frontline on my white boxer she got a horrible case of fleas. So before I put on the frontline I gave her a bath with dawn dish soap “works great for killing flea “ so we got rid of what was on her wait for her to dry and then put frontline on her by that night she was cover in flea again. I gave it a couple of weeks too work it did not so I thought maybe be I did it wrong so repeat the process of bathing and waiting for her to dry and repeat the frontline same thing happened. So I read view and it seem some people are having trouble with frontline not working. Somebody recommended K9 Advantix so I did the same thing that did with the frontline, gave her bath wait for her to dry and than applied the K9 Advantix and it worked great haven’t seen a flea on her in over a week! It also protect against mosquitoes too frontline does not! Price is comparable to frontline.
Images in this review
Customer image
Customer image
23 people found this helpful
Report