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K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 2-Mo Supply

4.5 4.5 out of 5 stars 39,487 ratings

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2 Pack
Large Dog only

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About this item

  • K9 Advantix II Large Dog 30-day treatment & prevention protects dogs 21-55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
  • Kills fleas within 12 hours of application
  • Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
  • Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
  • No prescription needed

Customer ratings by feature

Easy to use
4.2 4.2
Scent
3.7 3.7
Comfort
3.6 3.6
Sheerness
3.5 3.5

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K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 2-Mo Supply
K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 2-Mo Supply
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K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply
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Price-17% $32.00
List:$38.38
$79.98$54.99$14.99-12% $79.98
List:$91.18
-11% $57.48
List:$64.78
Delivery
Get it as soon as Monday, Mar 18
Get it as soon as Monday, Mar 18
Get it Mar 19 - 20
Get it as soon as Monday, Mar 18
Get it as soon as Monday, Mar 18
Customer Ratings
Easy to use
4.2
4.2
4.1
4.6
4.2
4.2
Value for money
3.4
3.4
3.2
3.6
3.5
3.4
Comfort
3.6
3.6
2.7
3.5
3.6
Scent
3.7
3.7
3.2
3.7
Sheerness
3.5
3.5
3.5
Sold By
5 Star Retailers
Amazon.com
Fannys Gifts
kingmo Pet
Amazon.com
Amazon.com
target audience
Dog
Dog
Dog
Dog
Dog
age range
7 weeks and older
7 weeks and older
7 weeks and older
All Life Stages
7 weeks and older
7 weeks and older
scent
Unscented
Unscented
Unscented
Unscented
form
Topical
Topical
Topical
Drops
Topical
Topical
volume
5 milliliters
1 quarts
4 milliliters
24 milliliters
10 milliliters
active ingredients
Imidacloprid, Permethrin, Pyriproxyfen
Imidacloprid, Permethrin, Pyriproxyfen
Imidacloprid, Permethrin, Pyriproxyfen
Fipronil 9.8%, (S)-methoprene 8.8%, OTHER INGREDIENTS 81.4%, TOTAL 100.0%
Imidacloprid, Permethrin, Pyriproxyfen
Imidacloprid, Permethrin, Pyriproxyfen

From the manufacturer

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Kills and Repels

Unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes for up to four weeks and also protects against biting flies and lice.

Same-Day Effectiveness

K9 Advantix kills fleas on dogs within 12 hours of application and prevents reinfestation.

Vet-Recommended

K9 Advantix is the leading brand in flea, tick and mosquito protection, recommended by veterinarians.

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Application key benefits

Easy-to-apply topical solution – no hard-to-swallow pills

Easy Application - Step 1

Holding the tube upright and pointed away from you and your pet, remove the cap from the applicator tube. Turn the cap around, place it back on the tube and twist to break the seal.

Easy Application - Step 2

Evenly apply the entire contents of the tube along the top of the dog’s back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of the dog (please refer to the product label). At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze a portion of the solution on the skin.

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K9 Advantix II Large Dog Seresto Large Dog Advantage II Large Dog advantus Advantage Treatment Shampoo
Form Topical Drops Collar Topical Drops Flea Soft Chew Tick and Flea Shampoo
Treatment or Prevention Treatment + Prevention Treatment + Prevention Treatment + Prevention Treatment Treatment
Application Frequency Monthly Every 8 Months Monthly Do Not Exceed One Soft Chew in a 24-hour Period See Product Label
Kills Fleas?
Kills Ticks?
Kills Mosquitos?
Kills Lice?
Starts to Kill Fleas Within 12 hours 24 hours 12 hours 1 hour On Contact

Product guides and documents

Product details

  • Is Discontinued By Manufacturer ‏ : ‎ No
  • Product Dimensions ‏ : ‎ 1 x 4.38 x 4.75 inches; 1.6 ounces
  • Item model number ‏ : ‎ 86314940
  • Date First Available ‏ : ‎ September 1, 2014
  • Manufacturer ‏ : ‎ Elanco US Inc
  • ASIN ‏ : ‎ B00N7DEBN4
  • Customer Reviews:
    4.5 4.5 out of 5 stars 39,487 ratings

Looking for specific info?

Product Description

K9 Advantix II Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh 21-55 lbs. to use K9 Advantix II Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. And, you can stock up with 2-dose, 4-dose and 6-dose packs so you never miss a monthly treatment. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Large Dog is a trademark of Elanco or its affiliates.

Top Brand: K9 advantix

Highly Rated
4.5/5 star rating from 100K+ customer ratings
Trending
100K+ orders for this brand in past 3 months
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Important information

Directions

Application Instructions: 1. Use only on dogs. DO NOT USE ON CATS or other animals. 2. The dog should be standing for easy application. Evenly apply the entire contents of the K9 Advantix® II tube to four to six spots on the top of the back from the shoulder to the base of the tail. 3. At each spot, part the hair until the skin is visible. 4. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. 5. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. 6. Do not get this product in your dog’s eyes, or allow your dog to ingest this product.

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Customer reviews

4.5 out of 5 stars
4.5 out of 5
39,487 global ratings

Customers say

Customers like the ease of application of the pet pest control product. They mention that it works well to repel ticks and fleas. They are also happy with the protection and effect on flea. However, some customers differ on durability, performance, value, side effects, and scratching.

AI-generated from the text of customer reviews

784 customers mention558 positive226 negative

Customers like the effect on flea. They say that the product really did prevent fleas, ticks, flies, and mosquitoes from feasting on their pets. They also say that it is the most effective tick repellent that they have used so far, and that it works by paralyzing the parasites. Some say that their pets have been using the product for 4 years and have never had any flea or tick bites.

"This is a great flea and tick! Would recommend for most any dog" Read more

"Works great. I use every month and have not had any bugs on my doggies even when it is high flea season." Read more

"...directly from FRONTLINE; indeed it was confirmed that FRONTLINE does NOT repel ticks...." Read more

"...It also protect against mosquitoes too frontline does not! Price is comparable to frontline." Read more

193 customers mention173 positive20 negative

Customers find the application of the pet pest control product to be easy. They mention that it works to repel ticks and fleas.

"Easy to apply and no vet bill. Used it for 3 months on 2 dogs, so far its done everything promised." Read more

"Ease of application and it works to repel ticks and fleas" Read more

"...Easy to apply, no scent at all and didn't irritate their skin at all." Read more

"...It’s easy to apply, and Dory seemed not to notice. She’s had it on for 2 days with no adverse effects. Thumbs up from me!" Read more

72 customers mention68 positive4 negative

Customers like the protection of the pet pest control. They mention it repels and protects their pets from fleas and ticks. They say it's effective and provides long-lasting protection against pests. It's safer than the cheap brands and is even safe for their puppy.

"Advantix 2 works great. It truly repels as advertised especially the mosquitos which is good since those are the thing to worry about heartworm...." Read more

"...The repel is SO KEY! Otherwise they still have to jump on the pet and bite them for the pesticide to work...." Read more

"...It's a reliable and effective product that provides long-lasting protection against pests and is safe for use on large dogs." Read more

"Protects against an array of things. I love that it's a simple treat too give the dogs each month." Read more

1,595 customers mention1,038 positive557 negative

Customers are mixed about the performance of the pet pest control product. Some mention that it works really well and very quickly, while others say that it lacks effectiveness and is not a great solution. Some customers also say that the product causes neurological weakness of their dog's hind end.

"...This was the most effective. Within 32 hours of an application, I saw the fleas fall off...." Read more

"I’ve used frontline for years and this time it did not work! Before I could get frontline on my white boxer she got a horrible case of fleas...." Read more

"Advantix 2 works great. It truly repels as advertised especially the mosquitos which is good since those are the thing to worry about heartworm...." Read more

"Works great. I use every month and have not had any bugs on my doggies even when it is high flea season." Read more

567 customers mention327 positive240 negative

Customers are mixed about the value of the pet pest control. Some say that it is a good price, while others say that its way too expensive and a waste of money. Some customers also mention that the product fell short of expectations and is not great for their dog.

"...Cheaper than the oral tablet you get a vet prescription for and easy to order with subscription" Read more

"...The idea of it is terrifying however, it is also expensive and for anyone struggling to spend that kind of money per month on their pup...." Read more

"...It also protect against mosquitoes too frontline does not! Price is comparable to frontline." Read more

"Pretty expensive" Read more

209 customers mention80 positive129 negative

Customers are mixed about the scratching. Some mention that it stopped their dog from itching, while others say that it irritates their skin. Some customers also mention that their dogs may be having an allergic reaction.

"...I noticed toward the end of the month she got itchier and even found a flea! Three weeks in, the treatment should still have kept going...." Read more

"...This helps spread it out and not irritate her and make her itchy. Then again, my pup has allergies and she's on Zyrtec daily...." Read more

"...I love the product and recommend it but be aware that it makes their backs itchy for the first 24 hours after application...." Read more

"...She does occasionally scratch at the collar but its not like nothing to be worried about...." Read more

143 customers mention75 positive68 negative

Customers are mixed about the side effects of the pet pest control product. Some mention that their pets have never had any side effects, while others say that some of the ingredients can have harmful long-term effects on their dogs and cats. Some customers also say that the medication has made their pets very sick.

"No problems w/side effects some people mention! Used for years and it works!" Read more

"Don't give this to your pet! It is awful. It is toxic. I gave this to my dog Charlie and he was just not himself for 2-3 months...." Read more

"...No weird side effects and helps them feel more comfortable for a month, even when the fleas are rampant in the summer heat...." Read more

"...this product that I’m aware of, although I’ve heard it can cause seizures in certain breeds (border collies in particular), so it’s worth talking to..." Read more

76 customers mention24 positive52 negative

Customers are mixed about the durability of the pet pest control. Some mention that it lasts more than a month, is reliable, and very strong, while others say that it doesn't last four weeks and that it does loose strength with age. There is no expiration date on the product, but it does lose its potency after 2 years.

"...As for K9 Advantix, I won't be buying it any longer because it doesn't last long and is not a controlled dosage like the collar." Read more

"Doesn't seem to last as long as it says." Read more

"...It's a reliable and effective product that provides long-lasting protection against pests and is safe for use on large dogs." Read more

"It killed fleas on my dogs but I found it didn't last the whole month. I have to reapply about three weeks after." Read more

No tick and fleas since we have been ordering.
5 Stars
No tick and fleas since we have been ordering.
I’ve been continuing this prescription for more than 6months and have not seen ticks or fleas on my dogs. I have a field in my backyard, and the dogs love playing outside even on rainy days. They usually would come back with ticks, in the summer especially. Since I’ve used this no more. On all 3 dogs. I have a German shepherd, shepherd mix, Chihuahua long hair. It’s only 1per package so I have to buy 3 every other month.
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Reviewed in the United States on February 19, 2024
Size: 2 PackStyle: Large Dog onlyVerified Purchase
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5.0 out of 5 stars It worked when Frontline did not!
Reviewed in the United States on August 15, 2023
I’ve used frontline for years and this time it did not work! Before I could get frontline on my white boxer she got a horrible case of fleas. So before I put on the frontline I gave her a bath with dawn dish soap “works great for killing flea “ so we got rid of what was on her wait for her to dry and then put frontline on her by that night she was cover in flea again. I gave it a couple of weeks too work it did not so I thought maybe be I did it wrong so repeat the process of bathing and waiting for her to dry and repeat the frontline same thing happened. So I read view and it seem some people are having trouble with frontline not working. Somebody recommended K9 Advantix so I did the same thing that did with the frontline, gave her bath wait for her to dry and than applied the K9 Advantix and it worked great haven’t seen a flea on her in over a week! It also protect against mosquitoes too frontline does not! Price is comparable to frontline.
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21 people found this helpful
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Reviewed in the United States on February 15, 2024
Size: 1 PackStyle: Large Dog onlyVerified Purchase
One person found this helpful
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Reviewed in the United States on January 2, 2024
Size: 2 PackStyle: Large Dog onlyVerified Purchase